Therapeutic focused ultrasound and tissue fields

Sound waves can be focused deep inside the body to heat tissue, open the barrier protecting the brain, or change nerve activity, without any cut. How the sound actually acts on cells and how to aim it through bone are open questions.

Why it matters

These are the only non-ionizing ways to deliver a controlled physical effect to a deep target, and both safety and dose control depend on the unresolved physics.

Review

Blackmore, Shrivastava, Sallet, Butler and Cleveland, Ultrasound neuromodulation: a review of results, mechanisms and safety, Ultrasound in Medicine and Biology, 2019. https://doi.org/10.1016/j.ultrasmedbio.2018.12.015 reference checked

Timestamp record

Signed record
8f240ebd4ecd…
Public log
Entry 272, in checkpoint 2,123
In the log by
Block 969,698, 2026-10-03

This text was in the PubPhys log by that date. The date says nothing about when the problem was first posed.

5 problems